A treatise on the nervous diseases of children, for physicians and students . al relationbetween these changes andothers pointing to a chronicinterstitial encephalitis, andthe disease proper. More-over, Golgis patient died atthe age of thirty-two years, andin him chorea was associatedwith chronic mental disease. Up to the present time the results of bacteriological research are not verypromising. Berkeley found the staphylococcus pyogenes aureus in culturesfrom the blood of a fatal case of chorea. Dana has published the history and autopsy of a case of chronic patient was thirty-fou
A treatise on the nervous diseases of children, for physicians and students . al relationbetween these changes andothers pointing to a chronicinterstitial encephalitis, andthe disease proper. More-over, Golgis patient died atthe age of thirty-two years, andin him chorea was associatedwith chronic mental disease. Up to the present time the results of bacteriological research are not verypromising. Berkeley found the staphylococcus pyogenes aureus in culturesfrom the blood of a fatal case of chorea. Dana has published the history and autopsy of a case of chronic patient was thirty-four years of age at time of death ; he had his firstattack of chorea at fourteen, and repeated attacks after that. The post-mortem findings included a chronic lepto-meningitis of the convexity of thebrain, hyaline bodies in the brain cortex, slight meningitis of the upper partof spinal cord, and slight meningoencephalitis. Diplococci were found inthe proliferating tissue between the meninges and the brain. The case is of unusual interest, showing that choreic symptoms may be. Fig. 46.—Changes in Purkinjes Cells in Chorea;Varicose Swelling of the Nerve-processes. (Golgi.) 124 THE NERVOUS DISEASES OF CHILDREN. associated with a wide-spread affection ; but the true pathology of chorea can-not be made out in any case of fourteen years standing, nor can such a casebe relied upon to prove the germ-theory of chorea. * The only just inference from the preceding account isthat the accurate pathology and morbid anatomy of choreaare still unknown. Of the changes that have been reportedby various writers, many, if not most of them, are secondaryand not primary. All that we can claim at present is thatthere is considerable change in the gray matter of thecentral nervous system ; that the entire motor tract may beinvolved, but that the changes occur more frequently in thecortex than in other parts of the brain. These choreiformmovements are often associated with gross lesions in thecortex ;
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Keywords: ., bookcentury1800, bookdecade1890, booksubjectnervous, bookyear1895
