The endemic diseases of the southern states . Typic eruption on backs of hands of gir! of sixteen. convinced of the correctness of their views, it seems to us thatall discussion as to the incubation period of pellagra is irrelevantuntil the etiologic factor of the disease has been scientificallydemonstrated. Skin S3Tnptoins.—While as stated above the symptoms ofthe gastro-intestinal tract are usually the first to be observed, itoften occurs that the skin eruption develops first. The mostfrequent time of the first occurrence of the skin lesions is in thespring, but they may develop first in the
The endemic diseases of the southern states . Typic eruption on backs of hands of gir! of sixteen. convinced of the correctness of their views, it seems to us thatall discussion as to the incubation period of pellagra is irrelevantuntil the etiologic factor of the disease has been scientificallydemonstrated. Skin S3Tnptoins.—While as stated above the symptoms ofthe gastro-intestinal tract are usually the first to be observed, itoften occurs that the skin eruption develops first. The mostfrequent time of the first occurrence of the skin lesions is in thespring, but they may develop first in the fall. Recurrences inthe fall following a spring eruption may occur. These manifestations are usually spoken of as an erythema. 328 ENDEMIC DISEASES OF THE SOUTHERN STATES but, as Fox^-- has pointed out, the erythema with which thelesions usually begin is of minor importance owing to the. Fig. 74.—Extensive and severe eruption on arms. comparatively short time it lasts, and dermatitis would be amore appropriate term. PELLAGRA 329
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