Domain swapped monellin protein, illustration

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Illustration of a monellin protein that has been engineered to promote domain swapping. Domain swapping is a process where two or more identical polypeptide chains, the simplest structure of a protein, exchange structural elements. The gene for this protein has been mutated so that a loop between two of the protein's beta-strands is deleted. This has lead to domain swapping in a protein that does not normally undergo this process. Monellin, from the fruit of the serendipity berry (Dioscoreophyllum cumminsii), is perceived as sweet by humans.

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Size: 4687px × 4706px
Location:
Photo credit: © FRANCISCO J. ENGUITA/SCIENCE PHOTO LIBRARY / Alamy / Afripics
License: Licensed
Model Released: No

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