Studies from the laboratories of the Deptof Surgery . ^^^ Pic. I.—Circulation of infants tiVjia and fibula. (After Lexer.) A, nutrient artery; B, metaphyseal and capsular arteries; C. relative avascular zone where sequestrum separation usually Fig. 2 (Path. No. 5665).—Opera-tion, October 10. 1919. Procedure:Capillary tube containing crotonoil inserted in medullary : Killed November 3, , sequestrum; Iji, involucrum;S, separation zone. agar. As croton oil causes marked necrosis of the surrcnmding bone, wewere able to produce a chemical osteomyelitis. A secjuestrum oft
Studies from the laboratories of the Deptof Surgery . ^^^ Pic. I.—Circulation of infants tiVjia and fibula. (After Lexer.) A, nutrient artery; B, metaphyseal and capsular arteries; C. relative avascular zone where sequestrum separation usually Fig. 2 (Path. No. 5665).—Opera-tion, October 10. 1919. Procedure:Capillary tube containing crotonoil inserted in medullary : Killed November 3, , sequestrum; Iji, involucrum;S, separation zone. agar. As croton oil causes marked necrosis of the surrcnmding bone, wewere able to produce a chemical osteomyelitis. A secjuestrum often 5 to10 cm. in length and including the entire circumference of the shaft fre-quently occurred. This sequestrum was separated from a newly formedinvolucrum by a zone of debris and leucocytes; therefore, all the factorsof an acute osteomyelitis were present with the exception jjrobably ofbacteria and their by-products. .Sections show the sequestrum with aninvolucrum surrounding CFigs. 2 to 7) but separated from it by a zoneof pus. The cortical bone of sequestrum shows absence of nuclei and 682 ACUTE H^MATOGEXOUS OSTEOMYEETTTS throughout its cancellous portion there is a marked inhltration of leuco-cytes. The involucrum consists of newly fonn
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Keywords: ., bookcentury1900, bookdecade1910, bookpublishernewyork, bookyear19
