. Kirkes' handbook of physiology . nded by the radiating fibrils of the attractionsphere, and some of these fibrils pass continuously fromone centrosome to the other, forming the achromaticspindle. At the same time the intranuclear network be-comes converted into a fine convoluted coil (spirem orskein) which may be either continuous or else broken up into several thread or threads then shorten and become thicker, while the convolutions,which have become less numerous, arrange themselves in a series of con-necting loops, forming the wreath. The nuclear membrane and the nucleolusdisa


. Kirkes' handbook of physiology . nded by the radiating fibrils of the attractionsphere, and some of these fibrils pass continuously fromone centrosome to the other, forming the achromaticspindle. At the same time the intranuclear network be-comes converted into a fine convoluted coil (spirem orskein) which may be either continuous or else broken up into several thread or threads then shorten and become thicker, while the convolutions,which have become less numerous, arrange themselves in a series of con-necting loops, forming the wreath. The nuclear membrane and the nucleolusdisappear, the latter passing at times into the cell protoplasm and disintegrat-ing. The wreath then breaks up into V-shaped segments, the chromosomes,of which each species of animal has a constant and characteristic varies in the different animals, but is sixteen in man. The two centrosomes migrate to the poles of the nucleus, while the achro-matic spindle which connects them occupies the long axis of the nucleus. The A B. Fig. is —Leucocyteof Salamander Larva,Showing AttractionSphere. (After Flem-ming.)


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