Practical pathology; a manual for students and practitioners . :-- /?A<. Fig. 21.—Section from a healing ulcer of the leg. Stained withalum hrematein and van Giesons stain. ( x 20.) a. Layer of fibrinous lymph and pus cells, mostly altered polymorpho-nuclear leucocytes lying on the granulating Invading margin of epithelium. c. Epithelial layer with well-formed papilla, due to dipping down of processes into spaces between loops of vessels. d. Connective tissue cells and active leucocytes near the surface and around the sections of transverse portions of vascular loops (f)./. Verti
Practical pathology; a manual for students and practitioners . :-- /?A<. Fig. 21.—Section from a healing ulcer of the leg. Stained withalum hrematein and van Giesons stain. ( x 20.) a. Layer of fibrinous lymph and pus cells, mostly altered polymorpho-nuclear leucocytes lying on the granulating Invading margin of epithelium. c. Epithelial layer with well-formed papilla, due to dipping down of processes into spaces between loops of vessels. d. Connective tissue cells and active leucocytes near the surface and around the sections of transverse portions of vascular loops (f)./. Vertical or limb parts of vascular loops passing to the ;n Groups of leucocytes around the young blood Older, more perfectly formed vessels shooting from the deeper Corium proper, composed of hard fibrous More cellular new tissue in which vessels still remain, although the new tissue is now covered in by a well-formed epithelial layer. HEALING ULCER 205 formation of a kind of epithelial barrier which, in some instances,. Fig. 22.—Granulating ulcer stained with alum ha-nialein andvan Giesons stain. ( x 300.) a. Fibrinous coagulated lymph at the surface of the Small round cell, probably a polymorpho-nuclear leucocyte. c. Spindle-shaped connective tissue cell. d. Vascular loop, transverse part. e. Vertical limb of same. Evidently formctl by double rows of elongated cells. f. Polymorpho-nuclear leucocytes, lymphocytes, and rt)unded con- nective tissue cells. g. Spindle-shaped connective tissue cells, fibroblasts. //. Transverse spindle-shaiied cells (with basket-work arrangement)which ultimately ftirm firm fibrous tissue and cause constrictionof many of the new vessels. interferes very materially with the healing of the wound. (Hamilton 2o6 INFLAMMATION, ORGANISATION, AND REPAIR gives this as one of the chief causes of the slow healing of ulcers.; III ^ * ISiP
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