. Diseases of infancy and childhood . than its unaffected neighbors, and to MALARIAL FEVER. CGZ be considerably decolorized. On the day oi the paroxysm the organism hasentirely filled and almost destroyed the red bhxxl-corpusch, which is j-ep-resented only by a faint pale rim about the IuU-grown parasite, if, indeed,it has not entirely disappeared. The pigment granules may show at thisstage a very active motion, but the amoeboid movements of the organismas a whole are but little marked. At the time of the paroxysm an interest-ing change takes place; the pigment gathers together in a more or le
. Diseases of infancy and childhood . than its unaffected neighbors, and to MALARIAL FEVER. CGZ be considerably decolorized. On the day oi the paroxysm the organism hasentirely filled and almost destroyed the red bhxxl-corpusch, which is j-ep-resented only by a faint pale rim about the IuU-grown parasite, if, indeed,it has not entirely disappeared. The pigment granules may show at thisstage a very active motion, but the amoeboid movements of the organismas a whole are but little marked. At the time of the paroxysm an interest-ing change takes place; the pigment gathers together in a more or lesssolid clump, usually in the center of the organism, while the rest of theprotoplasm looks somewhat granular and shows a suggestion of lines radiat-ing outward from the center. This appearance gradually changes, the linesbecoming more distinct, until finally we see the central clump of pigmentsurrounded by from fifteen to twenty small ovoid or round glistening seg-ments, each one having a central more refractive spot, and resembling. Fig. 218—Malaria Plasmodia; Ter-tian Type. Plehn-Chenzinskys 1000. Fig. 210.—Malaria Plasmodia; Trop-ical Form. Romanowsky-Xoelit 1000. strongly the hyaline bodies which we see immediately follow^ing the segmentation of the organism is always coincident with the paroxysm,and the presence of the blood of a segmenting body is a sure indicationthat the paroxysm is present, or is about to occur. Immediately followingthe paroxysm fresh hyaline bodies appear in the red corpuscles. Thoughthe invasion of the corpuscles by these fresh segments has never beenactually observed, the evidence that this occurs is so strong that we cansafely accept it as a fact. Besides these forms we see not infrequently suudlor large extra cellular pigmented bodies; that is, organisms reseuiblingexactly those within the red l)lood-corpuscles, exce})ting that they are freein the blood current. These may be seen at tinu^s to break up iuto several s
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