. Contributions to embryology. Embryology. THE DEVELOPMENT OF CERTAIN FEATURES OF THE CEREBELLUM. 373 In the case of hemiatrophy, the only point of interest Ls that we have in the vermis and right hemisphere a very marked hypertrophy secondary to the atrophy in the left hemisphere and also to an extent in the flocculus of both sides. OUTER NUCLEAR LAYER. The most prominent feature Of figure 1 is the transitory outer nuclear layer, which at this stage of development ( month of fetal life) occupies a most superficial position in the molecular layer. This outer molecular layer has recently


. Contributions to embryology. Embryology. THE DEVELOPMENT OF CERTAIN FEATURES OF THE CEREBELLUM. 373 In the case of hemiatrophy, the only point of interest Ls that we have in the vermis and right hemisphere a very marked hypertrophy secondary to the atrophy in the left hemisphere and also to an extent in the flocculus of both sides. OUTER NUCLEAR LAYER. The most prominent feature Of figure 1 is the transitory outer nuclear layer, which at this stage of development ( month of fetal life) occupies a most superficial position in the molecular layer. This outer molecular layer has recently been studied in Obersteiner's laboratory by Biach, and also by Lowy. Biach studied the time of disappearance of the layer in the human brain, and found a gradual decrease in the number of layers of cells until the whole dis- appeared, about the eleventh month. XCS^J \ \M^?,^<^^.^i^^ Lowy's study is comparative. He di- rects attention to the disappearance of the outer nuclear layer in different ani- mals at very different periods, corre- sponding to the ages at which myelinization in the cerebellum becomes pro- nounced and locomotion is acquired. He gives a very satisfactorj^ review of the various opinions which have been advanced as to what becomes of this outer nuclear layer, whether it goes to help form the inner nuclear layer or the Purkinje. Fig. 4.—Cross-section of the cerehellum of an embryo of 6 months, from the cortex of which figure 1 is Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Carnegie Institution of Washington. Washington, D. C


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