. A Reference handbook of the medical sciences embracing the entire range of scientific and practical medicine and allied science . y in spreading was the same year (1880) that Laveran discovered theintraglobular parasites now universally acknowledged asthe cause of malaria. The transference of these hfema-tozoa from one host to another bj means of mosquitoeswas conjectured as early as 1883 by King and in the fol-lowing year by Koch and Laveran: but was first actuallydemonstrated by Ross, in a scries of be-tween 1895 and 1899; these facts have been abundantlyconfirmed


. A Reference handbook of the medical sciences embracing the entire range of scientific and practical medicine and allied science . y in spreading was the same year (1880) that Laveran discovered theintraglobular parasites now universally acknowledged asthe cause of malaria. The transference of these hfema-tozoa from one host to another bj means of mosquitoeswas conjectured as early as 1883 by King and in the fol-lowing year by Koch and Laveran: but was first actuallydemonstrated by Ross, in a scries of be-tween 1895 and 1899; these facts have been abundantlyconfirmed by many subsequent investigators. In 1897JIacCallum first observed the sexual phase in the alliedavian ha^matozoa, and the further elucidation of the lifehistory of tlie parasite was biought about by contribu-tions of Ross, Bastianelli, Bignami, Grassi, and others,while unimpeachable evidence of the agency of the mos-quito in carrying the disease was furnished by thepositive infection experiments of JIanson, who imported Form, and arratigement <f the stales of the nape inAnoph-elsi. Megarhina. Culex. Stf4/omyia arid Fig. aSSi.—Grapbic Key to Scale Arrangement of Leading (ienera. (After Giles.) from Rome tertian infected Anopheles, which evoked thedisease in those whom they were permitted to bite inLondon. The connection of the mosquito with yellow fever,conjectured by Finlay of Havana as early as 1881, waiteduntil 1900 for its experimental demonstration in the in-vestigations of the Yellow Fever Commission, consistingof Drs. Reed, Carroll, Lazear, and Agramonte, in thecourse of which two members of the Connnission ac-quired the disease and one, Dr. Lazear, succumbed to it. Kinds of Mus<]uiioes.—It is necessary now to considerthe vaiious types of mosquitoes before taking up morespecifically their relations to disease. In all about threehundred species of mosquitoes have been described, ofwhich onl} thirtj-six species have been recorded inNorth Ameiica. Of these


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