. A text-book of practical therapeutics, with especial reference to the application of remedial measures to disease and their employment upon a rational basis . ). The drug acts as a depress-ant to the spinal cord (Pecholier),and it also depresses the heart ifgiven in large doses and retainedby the stomach long enough forit to be absorbed. Ipecac iseliminated by the kidneys, thegastro-intestinal mucous mem-brane, and the skin (Binz).If emetine is given in lethaldose to one of the lower animals, death is due to failure of —Ipecac is used as an emetic where a fairl
. A text-book of practical therapeutics, with especial reference to the application of remedial measures to disease and their employment upon a rational basis . ). The drug acts as a depress-ant to the spinal cord (Pecholier),and it also depresses the heart ifgiven in large doses and retainedby the stomach long enough forit to be absorbed. Ipecac iseliminated by the kidneys, thegastro-intestinal mucous mem-brane, and the skin (Binz).If emetine is given in lethaldose to one of the lower animals, death is due to failure of —Ipecac is used as an emetic where a fairly rapidaction is required. It is particularly useful where the stomach of achild is overloaded with food. In cases of poisoning it is hardlyactive or rapid enough as an emetic, and is not so good as mustard orsulphate of zinc. In babies and young children an attack of bronchitisoften causes digestive disorders by reason of the mucus coughed upfrom the lungs being at once swallowed instead of spat out of the these cases the stomach may be relieved and the state of the lungsimproved by the use of an emetic dose of syrup of ipecac, 2 to 3 drachms. A, vomiting centre in the medulla stimulatedby ipecac; B, nerves in mucous membrane ofstomach irritated by ipecac. IPECACUANHA. 291 (). Often if the dose be not large enough to produce emesis itwill purge the child and remove the mucus by the bowel. In some cases of obstinate vomiting small doses of ipecac will act asa most successful cure, provided that the vomiting is due not to inflam-mation and excitement, but to depression. The irritant effect of theipecac stimulates the depressed stomach to a normal tone. The properdose of ipecac for this purpose is J to \ grain () or lessevery half-hour until five or six doses are taken. In some cases of the vomiting of pregnancy it is very useful, in othersit utterly fails. 1 minim () of the wine or J to J grain ()of the powdered ipecac, repeated every
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