Pathology and treatment of diseases of women . gth of its existence may invade also more or less deeply the uter-ine wall. The latter of course tends to offer to the mucoid sarcoma arelatively long resistance. The surface epithelium also and the glands remain for a long time pre-served in the mucous membrane sarcoma, only the glands become pressedtogether and the epithelium is flattened to a cuboidal or even a flat form PATHOLOGY OF THE VAGINA AND UTERUS 303 (see Fig. 135); later they undergo complete destruction on account of thegrowth of the tumor. If the cases are left to themselves, the en
Pathology and treatment of diseases of women . gth of its existence may invade also more or less deeply the uter-ine wall. The latter of course tends to offer to the mucoid sarcoma arelatively long resistance. The surface epithelium also and the glands remain for a long time pre-served in the mucous membrane sarcoma, only the glands become pressedtogether and the epithelium is flattened to a cuboidal or even a flat form PATHOLOGY OF THE VAGINA AND UTERUS 303 (see Fig. 135); later they undergo complete destruction on account of thegrowth of the tumor. If the cases are left to themselves, the entire cor-pus is finally replaced by the new-formation, which also invades the cer-vix and the pelvic connective tissue, and clinically the same picture re-sults as in carcinoma. The mucous membrane sarcomata of the cervix are exceedingly rare,but they differ in essential points from those of the corpus. The tendency to polypoid proliferation, already present in the latter,increases to such an extent, that it comes to the formation of multiple. FlG. 136.—Sarcomatously Degenerated Uterine Myoma. Zeiss, Obj. AA, Oc. 2.) (Authors preparation. pedunculated grapelike tumors emanating from the mucosa of the cervixwhich soon proliferate through the external os uteri into the vagina andfinally almost fill the latter. They are almost always spindle cell sarco-mata, sometimes of a complicated structure, because transversely stripedmusculature and cartilage are found. The wall sarcomata of the uterus develop, as a rule, through sarco-matous degeneration of myoma already present, only in rarer cases aprimary wall sarcoma without myoma formation takes place. A great number of statistics of different authors have shown that 3to 4 per cent, of all myomata undergo sarcomatous degeneration. Themalignant formation always starts from the connective tissue of thetumors (see Fig. 136). The sarcomatous degeneration is usually as-sociated with a considerable and rapid increase in the size of the tum
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Keywords: ., bookcentury1900, bookdecade1, booksubjectgynecology, bookyear1912