. Clinical gyncology, medical and surgical. aryingnumber of epithelia, with nuclei augmented both in size and in this we note karyokinetic figures in the nuclei, indicating a morerapid outgrowth of the living matter within the protoplasm of the pronounced cases of adenoid cancer the tubules exhibit manifold convo-lutions, and frequently only one side of the wall of the contorted tubule MALIGNANT NEOPLASMS OF THE UTERUS. 603 is discernible, the rest having perished in a crowd of protoplasmic bodiesvarying in aspect from a small solid lump to a larger globular, nucl
. Clinical gyncology, medical and surgical. aryingnumber of epithelia, with nuclei augmented both in size and in this we note karyokinetic figures in the nuclei, indicating a morerapid outgrowth of the living matter within the protoplasm of the pronounced cases of adenoid cancer the tubules exhibit manifold convo-lutions, and frequently only one side of the wall of the contorted tubule MALIGNANT NEOPLASMS OF THE UTERUS. 603 is discernible, the rest having perished in a crowd of protoplasmic bodiesvarying in aspect from a small solid lump to a larger globular, nucleated,protoplasmic mass. Even at the height of this infiltration, which meansa transition to the medullary type, we frequently notice single or clustered,somewhat angular, bodies, vestiges of previous epithelia. 4. Medullary Cancer.—This is the most malignant form, and usuallyarises from an adenoid cancer (see Fig. 8), though any variety of cancer,including dermoid and scirrhus, may in the course of time be transformed Fig. 10. i ill ^nm. Medullary cancer of uterus, x 500.—C, C, fibrous connective tissue crowded with protoplasmicbodies; r, vein in transverse section; .V, y, epithelial nests; E, endogenous new formation of livingmatter. into medullary. The diagnosis of this form is easy enough so long aswe find vestiges of previous tabular glands, consisting of a single row ofcolumnar epithelia or clusters of such epithelia. It is difficult, or mayeven be impossible, when such vestiges are absent. In the latter instancewe meet with protoplasmic bodies of varying sizes and shapes closely packedtogether, holding, as a rule, only scanty, wide capillaries. These are thecases which were termed by former pathologists encephaloid tumors, owingto their resemblance to brain-tissue. Virchow first maintained that cancermay lose its histological characteristics and assume those of sarcoma, an G04 MALIGNANT NEOPLASMS OF THE UTERUS. assertion the correctness of which, originally much doub
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