Sidney Farber, American Pathologist
Farber, founder of Children's Hospital Cancer Research Foundation, with a young patient. No photographer credited, dated 1960. Sidney Farber (September 30, 1903 - March 30, 1973) was an American pediatric pathologist. He is regarded as the father of modern chemotherapy. He was a graduate of SUNY Buffalo in 1923. In the mid-1920s, Jewish students were often refused admission to US medical schools. Farber was fluent in German, so he undertook his first year of medical school at the Universities of Heidelberg and Freiburg in Germany. Having excelled in Germany, he entered Harvard Medical School as a second year student and graduated in 1927. While working at Harvard Medical School on a research project funded by a grant from the American Cancer Society, he carried out both the preclinical and clinical evaluation of aminopterin, a folate antagonist in childhood acute lymphoblastic leukemia. He showed for the first time that induction of clinical and hematological remission in this disease was achievable. He continued to make advances in cancer research, notably the 1955 discovery that the antibiotic actinomycin D and radiation therapy could produce remission in Wilms' tumor, a pediatric cancer of the kidneys. And it was during this period that he took his persuasive powers to a national stage. Beginning in the early 1950s he became a star presenter at Congressional hearings on appropriations for cancer research. A compelling speaker, he was very successful in his efforts. He died in 1973 at the age of 69. No photographer credited, dated 1960.
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