A treatise on the principles and practice of medicine . Bouillon Culture of Typhoid Bacilli before the Addition of DilutedTyphoid Serum. X 500. (After Cabot.) Serum diagnosis. FIG. 2. The Same, Five Minutes after the Addition of Typhoid Serum(dilution 1 to 10), showing Typical Clump Reaction. X 400. (Cabot.) TYPHOID FEVER 33 and it often develops late, e. g., not until the seventeenth or sixty-seventhday. Cabot found the reaction in 97 per cent, of 5978 typhoid Osiers series it appeared in 93 per cent, before the eighth day. Whenit appears in the first week, it is due to a silently de


A treatise on the principles and practice of medicine . Bouillon Culture of Typhoid Bacilli before the Addition of DilutedTyphoid Serum. X 500. (After Cabot.) Serum diagnosis. FIG. 2. The Same, Five Minutes after the Addition of Typhoid Serum(dilution 1 to 10), showing Typical Clump Reaction. X 400. (Cabot.) TYPHOID FEVER 33 and it often develops late, e. g., not until the seventeenth or sixty-seventhday. Cabot found the reaction in 97 per cent, of 5978 typhoid Osiers series it appeared in 93 per cent, before the eighth day. Whenit appears in the first week, it is due to a silently developing infection(Widal), i. e., the typhoid is more advanced than we appreciate. Thetest is most significant when it is absent early and develops later. Typhoidbacillemia decreases as the Widal develops. The Widal reaction isspecific; its occasional occurrence in icterus is probably due to a previousattack of typhoid. Some maintain that the reaction is not one of infec-tion, but one of immunity, agglutination becoming most marked towardthe end of the 5. Nervous Symptoms.—Typhoid was once called nervous fever(jebris nervosa, nervenfieber). The nervous system may b


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