. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. R3 The importance of research in infectious disease cannot be overstated. No single reason can explain our inability to eradicate or minimize the global impact of infectious agents on human health. In total, 25% of all deaths worldwide are caused by bacterial, viral, fungal, and parasitic pathogens. Every year, one to three million people die from malaria, a disease caused by the organism Plasmodium. Tubercu- losis infects one person every second, and over the coming decade, at least 30 million will die from the disease. The


. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. R3 The importance of research in infectious disease cannot be overstated. No single reason can explain our inability to eradicate or minimize the global impact of infectious agents on human health. In total, 25% of all deaths worldwide are caused by bacterial, viral, fungal, and parasitic pathogens. Every year, one to three million people die from malaria, a disease caused by the organism Plasmodium. Tubercu- losis infects one person every second, and over the coming decade, at least 30 million will die from the disease. The Global Infectious Disease Program is part of the MBL's Josephine Bay Paul Center for Comparative Molecular Biology and Evolution. Directed by Mitchell Sogin, the Bay Paul Center has an active research program with strong ties to infectious disease. Bay Paul Center scientists have contributed many important insights about the evolution of parasitic protists using modern genomic approaches. Recently they embarked upon the sequence analysis of the G/ard/a genome. Excluding bacterial patho- gens, Giardia is a principal cause of diarrheal disease in children and adults and therapeutic treatments for the parasite are almost as devastating as the disease itself. The availabil- ity of the Giardia genome may lead to the identification of novel treatments that have minimal side effects. The technology necessary to sequence entire genomes is found at very few institutions. The MBL's Global Infectious Diseases Program will build on the unique expertise of the Bay Paul Center to provide more traditional parasitologists the opportunity to expand their research and better apply genomics to their research areas. This blending of genomics and parasitology will create a uniquely produc- tive research environment and provide the catalyst for exciting new discoveries on the important pathogens. The MBL has a rich history in studying the basic science of parasitism and infectious disease. Twenty y


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Keywords: ., bookauthorlilliefrankrat, booksubjectbiology, booksubjectzoology