A manual of diseases of the nervous system . cervical; B,dorsal; C, lumbar regions of the cord. Theposterior columns are sclerosed in their wholeextent, except in the vicinitj of the neck ofthe horn in the cervical and lumbar regions,the degeneration being rather less intense inthe lumbar than in the other parts. In theantero-hiternl columns there is an annular zoneof sclerosis in the periphery of the cord, widen-ing in the region of tlie pyramidal tract. Infront of this tract the zone is in thedorsal region, and trifling in degree in the lum-bar. The grey matter is but little alfected
A manual of diseases of the nervous system . cervical; B,dorsal; C, lumbar regions of the cord. Theposterior columns are sclerosed in their wholeextent, except in the vicinitj of the neck ofthe horn in the cervical and lumbar regions,the degeneration being rather less intense inthe lumbar than in the other parts. In theantero-hiternl columns there is an annular zoneof sclerosis in the periphery of the cord, widen-ing in the region of tlie pyramidal tract. Infront of this tract the zone is in thedorsal region, and trifling in degree in the lum-bar. The grey matter is but little t For the sections from which the drawing is made I am indebted to Dr. Pitt(who prepared them) and the late Dr. Moxon, under whose care tiie patient died inGuys Hospital. The case (full details of which will be found in a recent volume ofthe Guys Hospital Reports) is one of a series of five cases (four brothers and asister) which I reported some years ago to the Clinical Society ( Clin. Soc. Trans.,vol. xiv, 1881, p. 1). U8 SPINAL and induration of the pons and medulla were found by Friedreich,with atropby of the cells of the post-pyramidal nucleus and some degeneration of the res-tiform bodies, but noneof the anterior pyra-mids. Corpora amy-lacea were present inthe hypoglossal of the cere-bellum was found inone case ; the colls ofPurkinje were dimin-ished in numbers, butshowed no sign ofatrophy or degene-ration.* Pathology.—Thedisease appai^ently oc-cupies a clinical andpathological positionbetween the combinedsclerosis described asataxic paraplegia andsimple tabes, resem-bling the former in thecommon affection of thelateral and posteriorcolumns, and the consequent weakness with ataxy—resembling it alsoin the imperfect limitation of the changes, and in the intensity of thosem the middle of the posterior columns in the dorsal region; but itdiffers from this, and resembles tabes, in the degree of affection of theposterior columns in the lumbar region
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Keywords: ., bookcentury1800, bookdecade1890, booksubjectnervoussystem, bookye
