A text-book of physiology for medical students and physicians . naryspinal nerve (fifth cervical)is sutured to the peripheralend of the cut vagus, it will,after time for regenerationhas been allowed, cause,when stimulated, the usualstoppage of the heart. The Course of the Ac-celerator Fibers.—Theheart receives efferent ormotor nerve fibers fromthe sympathetic system inaddition to those reaching it by way of the vagus nerve. Atten-tion was first called to these sympathetic fibers by Legallois(1812), but our recent knowledge dates from the experimentsmade by von Bezold (1862), which were afterwa


A text-book of physiology for medical students and physicians . naryspinal nerve (fifth cervical)is sutured to the peripheralend of the cut vagus, it will,after time for regenerationhas been allowed, cause,when stimulated, the usualstoppage of the heart. The Course of the Ac-celerator Fibers.—Theheart receives efferent ormotor nerve fibers fromthe sympathetic system inaddition to those reaching it by way of the vagus nerve. Atten-tion was first called to these sympathetic fibers by Legallois(1812), but our recent knowledge dates from the experimentsmade by von Bezold (1862), which were afterward completedby the Cyon brothers—M. and E. Cyonf—1866. These fiberswhen stimulated cause an increased rate of beat and are, there-fore, designated as the accelerator nerve of the heart. Their * Erlanger, American Journal of Physiology, 13, 372, 1905. | For the history and literature of the accelerator nerves, see Cyon, articleCceur, p, 103, in Richets Dictionnaire de Physiologie, 1900; or Tiger-stedt, Lehrbuch der Physiologie des Kreislaufes, 260, 1893,. Fig. 243.—Schematic representation of theeourse of the accelerator fibers to the dogs heart—right side.—(Modified from Pawlow.) the sym-pathetic nerve is represented in solid black. Thecourse of the accelerator fibers is indicated by ar-rows. /, Cervical sympathetic combined in neckwith, 10, the vagus; //, ///, IV, rami communi-cantes from the second, third, and fourth thoracicspinal nerves, carrying most of the accelerator fi-bers to the sympathetic chain; 7, annulus of Vieus-sens; 8, inferior cervical ganglion; 2, 3, 4, 5,branches from vagus and vago-sympathetic trunkgoing to cardiac plexus (some of these—3, 5,—carry accelerator fibers; 9, the inferior laryngealnerve. 584 CIRCULATION OF BLOOD AND LYMPH. course has been worked out physiologically in a number ofanimals. Among the mammalia and, indeed, among differentanimals of the same species there is some variation, but a generalconception of their origin and


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