AMAarchives of neurology & psychiatry . ocrine dysfunction in suchcases, particularlv of the suprarenal system. * From the State Psjchopathic Hospital, Ann Arbor, IMich. 1. Koo\-, F. H.: Hyperglycemia in Mental Disorder. Brain 42:214 (Oct.)1519. Raphael. and Parsons, J. P.: Blood Sugar Studies in Dementia Praecoxand Manic-Depressive Tnsanitj, Arch. Xeurol. & Psychiat. 5:687 (June) 1521. 2. Hamman, L., and Hirschman, I.: Studies on Blood Sugar—.AlimentaryHyperghxemia and Glycosuria as a Test of Sugar Tolerance. .Arch. Int. :762 (Dec.) 1517. 3. Cowie, D. 1\I., and Beaven, P. W.: On the
AMAarchives of neurology & psychiatry . ocrine dysfunction in suchcases, particularlv of the suprarenal system. * From the State Psjchopathic Hospital, Ann Arbor, IMich. 1. Koo\-, F. H.: Hyperglycemia in Mental Disorder. Brain 42:214 (Oct.)1519. Raphael. and Parsons, J. P.: Blood Sugar Studies in Dementia Praecoxand Manic-Depressive Tnsanitj, Arch. Xeurol. & Psychiat. 5:687 (June) 1521. 2. Hamman, L., and Hirschman, I.: Studies on Blood Sugar—.AlimentaryHyperghxemia and Glycosuria as a Test of Sugar Tolerance. .Arch. Int. :762 (Dec.) 1517. 3. Cowie, D. 1\I., and Beaven, P. W.: On the Clinical Evidence of Involve-ment of the Suprarenal Glands in Influenza and Influenzal Pneumonia, . Med. 24:78 (July) 1919. R--iPHAEL~PARSO\S~ STroIESPROCEDURE 173 cont^rn ne^ ^ , ^^ ^ ^ *= *ree normal controls, nme cases of dementm praecox (including simplex, hebe-phrenic, and catatonic types) and six cases of manic ,„tciud,ng three in the excited or agitated phase It^d. ,1,.;?^° ^ ° =PP-i glyce,„ia. The continuous l„,e blood sugar percentage in normal persons; the short and long da t L the long dashes, m manic-depressive (depressed) patients. tliree in tite depressed phase,. The psycltotic subjects were all in theacute phase of their specific disorders. fnl,^ IT P^^ ™P°J-^d in this study mav be detailed asfollows: After an overnight fast (6 p. m. to 7 a: m.), initial or 174 IRCIiniiS OF XnrROLOCY AXD ISYCIUATRV control blood samples were drawn and 1 mg. of epinephrin (1 ofepinephrin chlorid, Parke, Davis & Company) was administered intra-muscularly. Following this, blood samples were drawn after half anhour, one hour, two hours, three and one-half hours, five hours, andsix and one-half hours, and blood sugar determinations made essentiallyaccording to the Lewis-Benedict method, as described in full in anearlier paper by Raphael and Parsons.^ No food was given duringthe experimen
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