A text-book of practical therapeutics . ide, it makes a neutral sus-pension of the free base. If three molecular proportions of sodiumhydroxide are added it forms an alkaline solution, not a of these forms have been used. The alkaline solution is, however,the best. Before opening the ampoule it should be immersed in95 per cent, alcohol for fifteen minutes. If any opening is discov-ered that ampoule should be discarded. The following table may ARSPHENAMINE 135 be used to indicate the proportions of arsphenamine and sodiumhydroxide in 15 per cent, solution used for intravenous or
A text-book of practical therapeutics . ide, it makes a neutral sus-pension of the free base. If three molecular proportions of sodiumhydroxide are added it forms an alkaline solution, not a of these forms have been used. The alkaline solution is, however,the best. Before opening the ampoule it should be immersed in95 per cent, alcohol for fifteen minutes. If any opening is discov-ered that ampoule should be discarded. The following table may ARSPHENAMINE 135 be used to indicate the proportions of arsphenamine and sodiumhydroxide in 15 per cent, solution used for intravenous or intra-muscular use. Official 15 per cent, sodium hydroxide. gram. gram. = CC corresponding to drops. .. . = 23 .. . = 19 .. . = . 15 .. = 12 .. . = 8 Into a glass cylinder of 250 cc capacity, with a ground-glassstopper, put from 30 to 40 cc of cold, boiled, freshly-distilledwater1 (for caution see Intravenous Injection, Part III), and add. Fig. 15.—Apparatus for intravenous injection of arsphenamine. gram of arsphenamine. Shake thoroughly until dissolved, andadd about cc (23 drops) of 15 per cent, sodium hydroxidesolution. This forms a precipitate that redissolves on vigorousshaking. Add enough water to make 180 to 250 cc, adding a fewdrops of sodium hydroxide solution, if need be, to keep the solu-tion intact. Each 30 cc of the 180 solution contains gram ofarsphenamine. This is for intravenous use. 1 If the product is that of the Dermatological Research Laboratory use hot before adding sodium hydroxide. 136 DRUGS For intravenous injection a syringe may be used, but an apparatussuch as is commonly employed for the intravenous injection of normalsalt solution is much better. (See Fig. 15.) The injection shouldbe given very slowly over a period of eight minutes, while the patientis lying down, through a large hollow needle (No. 16 or 18) or a smallcannula, which is p
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