Antibiotic complexed with topoisomerase IV, illustration


Illustration of the antibiotic levofloxacin complexed with topoisomerase IV and DNA (deoxyribonucleic acid, blue helix) from a Streptococcus pneumoniae bacterium. Topoisomerase IV is a bacterial enzyme that untangles newly replicated DNA and enables the segregation of daughter chromosomes during replication. Levofloxacin binds to topoisomerase IV and inhibits it, therefore preventing the bacterium from replicating.


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Photo credit: © FRANCISCO J. ENGUITA/SCIENCE PHOTO LIBRARY / Alamy / Afripics
License: Licensed
Model Released: No

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