Transactions of the Royal Society of Edinburgh . ca decandra) grows abundantly in the UnitedStates. The root is the part employed; and in small doses it is said to act asan alterative, and has been highly recommended in chronic rheumatism. Inlarge doses it produces excessive vomiting and purging, with great prostrationof strength, and sometimes with convulsions {Op. x. p. 646). The preparationvol. xxix. part i. 3 i 214 PROFESSOR RUTHERFORD ON THE employed by us was a substance termed phytolaccin, prepared from the rootof the plant by Keith & Co. of New York, after the same manner as meni-sperm
Transactions of the Royal Society of Edinburgh . ca decandra) grows abundantly in the UnitedStates. The root is the part employed; and in small doses it is said to act asan alterative, and has been highly recommended in chronic rheumatism. Inlarge doses it produces excessive vomiting and purging, with great prostrationof strength, and sometimes with convulsions {Op. x. p. 646). The preparationvol. xxix. part i. 3 i 214 PROFESSOR RUTHERFORD ON THE employed by us was a substance termed phytolaccin, prepared from the rootof the plant by Keith & Co. of New York, after the same manner as meni-spermin (page 210). The dose for a man is from one to three grains. Thephysiological actions of phytolacca have not hitherto been investigated. Experiment 58. Dog that had fasted eighteen hours. Weight 31*1 kilo-grammes (fig. 58.)—Two grains of phytolaccin triturated with 2 cc. of bile and4 cc. of water were injected into the duodenum at p. The subsequent excitementof the liver was unequivocal. When the increase of secretion was well declared,. Experiment 58. Secretion of bile per 15. Secretion of bile per kilogramme of Secretion of bile per 15. Secretion of bile per kilogramme of dog: per hour. dog: per hour. ec. cc. 1-100-85 2-00a 1 0-244 cc. 0-90 1-80 1-10 ] 2-25 1-301-20 U-144cc. a 1-90 v — J 2-20 1-45 2-80 1-55 a 1-65 2-40 1-85 2-35 ^ 1-851-90 2:35 L 0-299 cc. 1-901-90 I 0-244 cc. 2-30 J Fig. 58.—Secretion of bile before and after phytolaccin andatropia. 2 grains of phytolaccin in 2 cc. of bile and4 cc. of water injected into the duodenum &tp; l-10thof a grain of atropia sulphate injected into the jugularvein at a, a, a, and a. one-tenth of a grain of atropia sulphate dissolved in ten minims of water wasinjected into the jugular vein at a, and again at a, a, a—in all four-tenthsof a grain; but the stimulating effect of the phytolaccin was not antagonisedthereby. Had this experiment been performed after instead of before Experi-ment 53, a larger dose of atropia would hav
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