. History and pathology of vaccination. ent up in a small cottage. It was the abode ofwretchedness, had the addition of pestilence been wanting. Hewas infected, of course ; and his recovery is very doubtful. I amtold to-day that he is very full of an eruption, the appearance ofwhich stands midway between Small Pox and Chicken Pox. Thishas been spoken of by some of the Dublin and Edinburghauthors. The outbreaks of Small Pox in various parts ofthe country, and the failures of vaccination, ledJenner to send a circular letter, early in 1821, to theprofession, endeavouring to arouse attention to th


. History and pathology of vaccination. ent up in a small cottage. It was the abode ofwretchedness, had the addition of pestilence been wanting. Hewas infected, of course ; and his recovery is very doubtful. I amtold to-day that he is very full of an eruption, the appearance ofwhich stands midway between Small Pox and Chicken Pox. Thishas been spoken of by some of the Dublin and Edinburghauthors. The outbreaks of Small Pox in various parts ofthe country, and the failures of vaccination, ledJenner to send a circular letter, early in 1821, to theprofession, endeavouring to arouse attention to thosepoints in vaccination which he considered essential toafford protection. Even the most ardent supporters ofvaccination would now only claim that vaccinationmodified an attack of Small Pox in future, butJenners original opinion remained unchanged. No-thing would shake his belief that persons vaccinatedwere for ever after secure from the infection ofSmall Pox. On the back of an envelope datedJanuary 14th, 1823, he wrote:— PLATE SMALL POX AFTER PERFECT VACCINATION (MONRO). ■/Jm-ir -At/, f C-m /,/, LIFE AND LETTERS. 249 My opinion of vaccination is precisely as it was when I firstpromulgated the discovery. It is not in the least strengthened byany event that has happened, for it could gain no strength ; it isnot in the least weakened, for if the failures you speak of had nothappened, the truth of my assertions respecting those coincidenceswhich occasioned them would not have been made out. On January 23rd, he wrote to his friend Gardner:— I have an attack from a quarter I did not expect, the Edin-burgh Review. These people understand literature better thanphysic ; but it will do incalculable mischief 1 put it down at100,000 deaths, at least. Never was I involved in so manyperplexities. Two days afterwards, he had an attack of apoplexy,which proved fatal the following morning, January26th, 1823. Before I make any further remarks upon thehistory of Cow Pox inoculation,


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