. Calcified tissues; proceedings. Bone; Collagen; Calcification. 66 E. RuTiSHAUSER et al.: Studies of the Non-inflammatory Vascular Pannus. Fig. 4. Series III. Rabbit n<. t, 2\ d i) â , lln mentum teres. To the left, marrow hardly altered, activ marrow (reticulosis). An avascular surface pannus. Alt 2 cartilaginous cys the ici;iun nt the insertion of the liga- mopoiesis. To the right, ischemic alterations of the f the cartilage due to humoral derangement, ble Discussion The aim of reproducing relatively simple examples of vascular pannuses was only partly attained in the experiments of Seri
. Calcified tissues; proceedings. Bone; Collagen; Calcification. 66 E. RuTiSHAUSER et al.: Studies of the Non-inflammatory Vascular Pannus. Fig. 4. Series III. Rabbit n<. t, 2\ d i) â , lln mentum teres. To the left, marrow hardly altered, activ marrow (reticulosis). An avascular surface pannus. Alt 2 cartilaginous cys the ici;iun nt the insertion of the liga- mopoiesis. To the right, ischemic alterations of the f the cartilage due to humoral derangement, ble Discussion The aim of reproducing relatively simple examples of vascular pannuses was only partly attained in the experiments of Series I and II. The involvement of the articular regions in the circulatory disturbances produced by the injection methods (Series I) is inconstant. When the patella is isolated from its lateral vascular connections (Series II), an effective collateral circulation develops and starts to normalize the local condition after 4 weeks. However, this technique seems to us to be the most satisfactory. The operation is simple and does not entail a direct interference with articular function. The division of the femoral neck initiates a pathological condition which resembles that described by Rokkanen (1962) in his excellent monograph. Experiments of immobilization and remobilization have been carried out by Mastro- MARiNO and Maiotti (1956) on the rabbit and by Evans et al. (1960) on the rat. Here again the histopathological picture resembles that which we have described; however, these authors reach more limited conclusions than those to which our find- ings have led us. In any case, their method is even more complicated than ours. Conclusions Articular ischemia achieved in the rabbit by different experimental procedures resulted in a typical transformation of the joints concerned. The terminal plate was simultaneously eroded by outgrowths of periosteal and synovial tissue (surface or intra-articular pannuses) and by sprouts of vasculo-reticular tissue from the marrow spaces (internal o
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