Gynaecology for students and practitioners . n of tubular projections from the lumina ofthe glands. These crypts, communicating with the lumen of anoriginal tubule, begin to branch and elongate, and may join up withothers which have arisen from another site ; hence a complex adeno-matous formation is produced. Some of the secondary tubules mayproject into the lumina {inverting type), but for the most part theyspread outwards in the fibromuscular stroma, which becomes graduallydiminished by the invasion of these ramifying tubules. There is nomarked tendency to multiplication of layers, so that
Gynaecology for students and practitioners . n of tubular projections from the lumina ofthe glands. These crypts, communicating with the lumen of anoriginal tubule, begin to branch and elongate, and may join up withothers which have arisen from another site ; hence a complex adeno-matous formation is produced. Some of the secondary tubules mayproject into the lumina {inverting type), but for the most part theyspread outwards in the fibromuscular stroma, which becomes graduallydiminished by the invasion of these ramifying tubules. There is nomarked tendency to multiplication of layers, so that for the most part CANCER OF THE CERVIX 525 the lumina possess only a single layer of cubical epithelium {see ). This type of cancer is rare in the cervix; it resembles in itshistology the so-called adenoma malignum (tubular carcinoma) of theuterine body. The histological evidence of malignancy consists,mainly, in the invasion and destruction of the stroma by the pro-liferating tubules. This growth has, however, but little tendency to. Fig. 276. Carcinoma of the Cervix. The cancer has arisen in an epithelial covering (1) is proliferatgd and stratified; the deep pseudo-glands(?) show the same characters ; alveoli packed with cancer-cells are seen at (3). invade the parametrium and the adjacent viscera ; it is therefore farless malignant than the squamous-celled cancer. In a few cases adeno-carcinoma of the cervix shows the same colloiddegeneration of cells as is seen in cancer of the bowel. Macroscopic Appearances of Cancer of the Cervix. The naked-eye appearances of cancer of the cervix are very variable. The youngerthe subject, the softer, more brain-like, and more malignant is thegrowth. Roughly speaking, cancers of the cervix uteri may be dividedinto those which show, from the first, a tendency to erode or ulcerate,and those which are characterized by a marked degree of new forma-tion or proliferation. Such a division into types, (1) ulcerative, and(2) prol
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Keywords: ., bookcentury1900, bookdecade1910, booksubjectgynecology, bookyear1
