A treatise on the nervous diseases of children, for physicians and students . r and rectum, and changes in elec-trical reaction are entirely such a variety of symp-toms is possible in this disease willbe understood easily enough whenwe refer to the morbid course of multiple cerebro-spinal sclerosis is slow, and thoughinvariably leading to a fatal issue,death is, in the majority of cases,the result of some intercurrent dis-ease. Etiology. — Disseminated scle-rosis comes on most frequently afteracute infectious diseases, after pow-erful emotions, and occasionally af-ter t


A treatise on the nervous diseases of children, for physicians and students . r and rectum, and changes in elec-trical reaction are entirely such a variety of symp-toms is possible in this disease willbe understood easily enough whenwe refer to the morbid course of multiple cerebro-spinal sclerosis is slow, and thoughinvariably leading to a fatal issue,death is, in the majority of cases,the result of some intercurrent dis-ease. Etiology. — Disseminated scle-rosis comes on most frequently afteracute infectious diseases, after pow-erful emotions, and occasionally af-ter traumatic injuries. Oppenheimhas shown that the disease appearsafter intoxication by metallic poi-sons, while Marie believes it to beinvariably of infectious origin, com-ing on after typhoid fever, pneumonia, measles, scarlatina,and small-pox. Heredity is supposed to play an important role in the eti-ology of insular sclerosis. In the broader sense it is true;for multiple sclerosis may indeed affect children who aredescended from a neurotic stock; but it is extremely rare. Fig 85. — Degeneration of theCauda Equina in MultipleSclerosis. (After Taylor. ) DISSEMINA TED SCL ER OSIS. 349 to find the disease in both parent and child. The cases ofPelizaeus, quoted approvingly by some authors, are not tomy mind typical cases of multiple sclerosis; they belongrather to the hereditary form of spastic paralysis. (Seepage 391.) Pathological Anatomy.—We can infer from the namethat the chief lesions in this disease are irregular scleroticpatches distributed throughout the greater part of the cen-tral nervous system. These patches sometimes occur in thebrain as well as in the spinal cord ; but there is no rule de-


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Keywords: ., bookcentury1800, bookdecade1890, booksubjectnervous, bookyear1895