Manual of pathology : including bacteriology, the technic of postmortems, and methods of pathologic research . l^. Fig. 376.—Thyroid Showtnt, Double Pyra-mid.—{Marshall, courUsy oj Dr. Richardson.) Imc. 377.—Thyroid Gland, Absence of IsthmusWITH Pyramid on Left Side. — (Marshall,courtesy oj Dr. Richardson.) well-known fact that occasionally cases of thyroid enlargement associatedwith exophthalmos, tremors, and rapid cardiac action (Gravess disease)show a progressive diminution in the size of the thyroid, which after-ward remains small. The phenomena brought about by ])rogressiveatrophy


Manual of pathology : including bacteriology, the technic of postmortems, and methods of pathologic research . l^. Fig. 376.—Thyroid Showtnt, Double Pyra-mid.—{Marshall, courUsy oj Dr. Richardson.) Imc. 377.—Thyroid Gland, Absence of IsthmusWITH Pyramid on Left Side. — (Marshall,courtesy oj Dr. Richardson.) well-known fact that occasionally cases of thyroid enlargement associatedwith exophthalmos, tremors, and rapid cardiac action (Gravess disease)show a progressive diminution in the size of the thyroid, which after-ward remains small. The phenomena brought about by ])rogressiveatrophy of the organ usually are identical with those seen after theremoval of the thyroid gland, the results of which have been studiedin man, monkeys, and other animals. The phenomena occurring in the patient are somewhat ditTerentwhen the thyroid gland has never been present—a condition constitut-ing sporadic cretinism, or congenital myxedema. The general )anccs uf nutrition and arrest of developmentare usuallv not evident at birth, but commonlv manifest themselves y-8 SPECIAL PATHOLOGY. within t


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