Sol Spiegelman, American Molecular Biologist
Sol Spiegelman (1914-1983) was an American molecular biologist whose pioneering discoveries accelerated the study of gene mechanisms and laid the foundations of recombinant DNA technology. His early work on enzymatic induction in yeasts demonstrated a new way to investigate how genes work. Later he developed RNA-DNA hybridization, one of the most important techniques of molecular biology, and in 1965 became the first to synthesize biologically competent and infective virus RNA in test tubes. He received a Lasker Award in 1974 for this work. From 1969 to 1983, he did innovative work on viruses that cause various cancers, developing new analytical techniques and increasing scientific understanding of retroviruses.
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