. Quain's elements of anatomy . llicle, and theovLun is thus in a manner attached at this place to the wall of the follicle(see fig. 613). In the largest follicles the chief difference in the contentsof the follicle consists in the far greater accumulation of the liquor folliculi,and in the multiplication of the epithelium-cells—both those which linethe follicle (membrana granulosa) and those which invest the ovum (discusproligerus)—so that each of these parts consists, in large foHicles, ofseveral layers of cells, mostly rounded or irregular, but columnar next thewall of the follicle and the
. Quain's elements of anatomy . llicle, and theovLun is thus in a manner attached at this place to the wall of the follicle(see fig. 613). In the largest follicles the chief difference in the contentsof the follicle consists in the far greater accumulation of the liquor folliculi,and in the multiplication of the epithelium-cells—both those which linethe follicle (membrana granulosa) and those which invest the ovum (discusproligerus)—so that each of these parts consists, in large foHicles, ofseveral layers of cells, mostly rounded or irregular, but columnar next thewall of the follicle and the exterior of the ovum respectively. The larger follicles have a very distinct wall, which is continuous withand derived from the stroma of the ovary, and is separable into two GRAAFIAN FOLLICLES. 719 parts, an inner containing the ramifications of the capillary blood-vessels,which are abundantly distributed to the larger foUicles, but nowherepenetrate amongst the epithelium cells; and an outer part more fibrous, in Fig. Fig. 615.—Section; of the ovary of an adult bitch (Walcleyer). \^ a, germ-epithelium ; h, egg-tubes ; c, c, small follicles ; cl, more advanced follicle ;e, discus proligerus and ovum ; /, second ovum in the same follicle (this occurs butrarely) ; g, outer tunic of the follicle ; h, inner timic ; i, membrana granulosa; Tc, collapsedretrograded follicle ; I, blood-vessels ; m, m, longitudinal and transverse sections of tubesof the parovarium; y, involuted portion of the germ-epithelium of the surface ; z, place ofthe transition from peritoneal to germinal or ovarian epithelium. which the larger branches of the blood-vessels of the follicle run. In bothlayers of the follicular wall, the cells are similar to those of the generalstroma, interstitial cells occurring abundantly; but it is uncertain whetherthere are any cells present of the nature of muscular fibres. The smallerblood-vessels running round the follicle from below, and minutely sub-divided on
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