. Archives of physical medicine and rehabilitation . tion; lis sont dans dautres cas rem-places par: brulures, corps etrangers, lesionsulcereuscs. agents physiques ou chimiquescapables de preparer le terrain a un viruscancereux. et ce terrain lui-meme lorsquilsagit de cancers epitheliaux nest reellemeniprepare et apte a etre ensemence qua parlird un certain age. These curious facts to which I havereferred and which appear to sustainBon els hypothesis are: (I) The ratsliver may be full of cysts (a dozen ormore) each containing the parasiticworm, and yet no sarcoma may develop;(2) when the tumor
. Archives of physical medicine and rehabilitation . tion; lis sont dans dautres cas rem-places par: brulures, corps etrangers, lesionsulcereuscs. agents physiques ou chimiquescapables de preparer le terrain a un viruscancereux. et ce terrain lui-meme lorsquilsagit de cancers epitheliaux nest reellemeniprepare et apte a etre ensemence qua parlird un certain age. These curious facts to which I havereferred and which appear to sustainBon els hypothesis are: (I) The ratsliver may be full of cysts (a dozen ormore) each containing the parasiticworm, and yet no sarcoma may develop;(2) when the tumor does appear, itoccurs not in each one of these worm-irritated cysts but as a rule only in one;exceptionally in two or three, veryrarely in four or five; (3) the begin-nings of the sarcoma are even verv muchmore restricted than this would indi-cate in that only one small area of thecyst wall or at most a few small spotsare at first involved. Moreover, whileBridre saw the Cysticercus in 8,000 309 TWENTIETH CEXTURY ADVANCES IN CANCER RESEARCH—SMITH. hit;. N— on Bryophyllum calycinum showiiiK abor-llvf MliootH, iiliorlive itiols. ^niil dlslnrl Inns ol le;ivcs due tothe Ktowlli of the tuniurs. Iliip Ntnilii. Needle prick Inoeula-lloiiH of iy20 and 1921. A—Hunch of dwiiifed slioots In iin axillary luinor. Inocu-lated Mav II, l!)Ll. Photo, Auk. 15, IJLl, xTi. Only aboutone-llfih of the tumor Im vUlble. B—Groups of lU XX111 II midrib tumor. Inoculated June L:t, (I. Photo, Nov. IS. rj^O. .\.i. C—Leal Ills stiowniK li-e to niutntitumors, lnoculntion^< of .NatUfiU sixc. S—Hoots de-veloping from an axillary sleiii-tumor. about twomonths. Photo, .June 4, 1920. For further evidence of effect of crowii-Knll stimulus onKryophyllum see Jour. Agr. Research, July 15. lUJl. and forM. Levlnes paper see Bull. Torrey Bot. Club. if<: No. 11, I ;i I ;i 310 TWENTIETH CENTURY ADVANCES IN CANCER RESEARCH—SMITH rats out of 2
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