The Journal of nervous and mental disease . globulin ± ; salvarsan—2 injections. Summary: Tabetic symptoms first with slight impairment ofvision and finally a psychosis. Whole period of symptoms, fouryears. Posterior column sclerosis definite—optic nerve changesfaint. HISTOLOGICAL STUDY OF OPTIC NERVES 227 Of the nonsyphilitic, the arteriosclerotics led, and the mostcharacteristic change in the nerves was a degeneration about thecentral artery of the retina in the optic nerve (see Fig. 2). One case of more than usual interest was: B. S. H. No. 11321, Path. —Female. Age 52 laundre


The Journal of nervous and mental disease . globulin ± ; salvarsan—2 injections. Summary: Tabetic symptoms first with slight impairment ofvision and finally a psychosis. Whole period of symptoms, fouryears. Posterior column sclerosis definite—optic nerve changesfaint. HISTOLOGICAL STUDY OF OPTIC NERVES 227 Of the nonsyphilitic, the arteriosclerotics led, and the mostcharacteristic change in the nerves was a degeneration about thecentral artery of the retina in the optic nerve (see Fig. 2). One case of more than usual interest was: B. S. H. No. 11321, Path. —Female. Age 52 laundress, who presented certain vague and anomalous mentalsymptoms, with no neurological findings which suggested thecause of her illness. Ophthalmoscopic examination was notmade during her life. Suddenly she fell dead while arrangingher hair after dinner. There were inequalities in the optic discsthen; one showed central cupping rather deeper than physiologic,the other showed a large gray protruding disc tentatively calleda choked Fig. S. Unilateral retrobulbar cyst with degeneration. B. S. H. Weigerts myelin sheath method. Postmortem, the left internal carotid had been aneurysmaland had burst. Before this it had pressed on the left optic nerve,producing atrophy sufficient to allow blood to ascend into thesheath of the nerve and produce the picture as outlined (see ). (To be reported in detail.) Of other lesions, the following is representative:B. S. H. No. 10873, Path. —Male. Age 43 yrs. At41 had right breast removed for carcinoma, after a swelling of15 years duration; recurrence within two years at site and overtrunk; began at this time to be different mentally; had delusionsof persecution, and was shortly sent to hospital, where he beganhaving convulsions. Pupils react sluggishly. History of con-vulsions. Thickness of speech. Mouth drawn to left Increasing number of convulsions. Inequality ofoptic fundi. Unilateral choked


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Keywords: ., bookcentury1800, bookdecade1870, booksubjectpsychologypathologic