. A practical treatise on diseases of the skin, for the use of students and practitioners. ion of molluscumcontagiosum (epitheliale) show that it is formed by a number of diverg-ing flask-shaped lobules, the small end of each opening into a common central cavity. The lobules are separatedFlG- 50- from each other by a thin fibrous partition, which may occasionally be demonstrated tobe the remains of a papilla. The entiremass or group of lobules is surrounded,except at the surface-opening, by a fibrouscapsule, thus giving the entire structurean appearance very similar to that of asebaceous gland


. A practical treatise on diseases of the skin, for the use of students and practitioners. ion of molluscumcontagiosum (epitheliale) show that it is formed by a number of diverg-ing flask-shaped lobules, the small end of each opening into a common central cavity. The lobules are separatedFlG- 50- from each other by a thin fibrous partition, which may occasionally be demonstrated tobe the remains of a papilla. The entiremass or group of lobules is surrounded,except at the surface-opening, by a fibrouscapsule, thus giving the entire structurean appearance very similar to that of asebaceous gland. The belief, formerlyheld by some observers, that the processMolluscous corpuscles. originated in the sebaceous gland, is now (After Kaposi.) known to be erroneous. Minute examina- tion fails to find any trace of a sebaceousgland in these formations. Their exact origin is still a disputed ques-tion. It is quite probable that they occasionally originate in the 1 Journal of Cutaneous and Venereal Diseases, August, 1886. 2 Journal of Cutaneous and Genito-Urinary Diseases, February, HYPER TR OPHIES. 431 epithelium lining the mouths of the follicles, but in the majority ofeases it is now believed that the process begins as a proliferation ofepithelial cells in the lower layers of the rete. The growth is confinedto the rete, from which the flask-shaped processes are pushed out,causing a flattening and more or less complete disappearance of theunderlying papillae. Each lobule is lined with a layer of palisade-cells continuous withthe same layer in the healthy rete adjoining the growth, and is filledwith round and cuboidal nucleated epithelium undergoing peculiarchanges. The first two or three rows of cells are usually normal, butabove them the changes become gradually more and more exact nature, sequence, and signification of these changes are indispute, but it would seem to be fairly well established that the outerpart of the cell shows early in the process abundan


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Keywords: ., bookauthorhydejamesnevins184019, bookcentury1800, bookdecade1890