. American journal of physiology. hensalt solution is perfused.) Thevein flow is practically abolished,even when the viscidity has beengreatly reduced by laking and, „ . , dilution. Serum, since it is much vein and ureter now are given as drops per minute; the oncometer in centimetres JGSS VISCIU, nas mucn lesS ettecton an arbitrary scale. Blood 1:3 sig-nifies one part of defibrinated blood andthree parts of 1 per cent sodium chloridesolution. NaCl signifies 1 per centsodium chloride solution.) The verticallines limit the beginning and end of eachperfusion. 60 22 40 18 20 14 0 10Time Figure 1.
. American journal of physiology. hensalt solution is perfused.) Thevein flow is practically abolished,even when the viscidity has beengreatly reduced by laking and, „ . , dilution. Serum, since it is much vein and ureter now are given as drops per minute; the oncometer in centimetres JGSS VISCIU, nas mucn lesS ettecton an arbitrary scale. Blood 1:3 sig-nifies one part of defibrinated blood andthree parts of 1 per cent sodium chloridesolution. NaCl signifies 1 per centsodium chloride solution.) The verticallines limit the beginning and end of eachperfusion. 60 22 40 18 20 14 0 10Time Figure 1. — Effect of blood and serum onthe dead kidney (Experiment 104). (Gen-eral explanation of the figures: ^^-^ = vein flow; = ureter flow; = oncometer. Unless otherwise stated, the (see Fig. i). The same phe-nomena are produced when thekidney vessels are dilated by 2per cent sodium chloride solu-tion. Perfusion Experiments 07t Excised Kidneys. 293 C. General Phenomena of the Perfusion of RecentlyExcised Kidney with Blood. 03 = 6. The typical phenomena are shown in Fig. 2. From this it maybe seen that the vein flow is suddenly increased, the maximum beingusually attained within five minutes. There is then a sharp returnof the vein curve toward a constant, which isgenerally reached within fifteen or twentyminutes. This constant is usually about thelevel of the original vein flow, but may beeither above or below. The oncometer shows a sharp and severefall from the start. This is quite indepen-dent of any changes in the vein flow. (Theslight irregularity in the figure is unusual,and probably accidental.) The ureter flow also shows a sharp andconspicuous decrease, being always reducedto a very few drops. In most cases this isfollowed by a slight improvement when thevein flow diminishes, as shown in the figure. As I have indicated in the introduction,these typical changes of the vein flow are not obtained in every experiment, because there are a number of inter-fering factors. The d
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