. Pathogenic micro-organisms, including bacteria and Protozoa; a practical manual for students, physicians and health officers. of the growthof the colonies. In many cases after a time concentric rings, in-creasing from day to day, appear in the zone of liquefaction. (SeeFigs. 144 and 145.) Examined under a low-power lens, at the endof sixteen to twenty-four hours, the colonies appear as small, light THE CHOLERA SPIRILLUM. 445 yellow, round, coarsely granular disks, with a more or less irregularoutline. In many cases at this stage an ill-defined halo is seen tosurround the granular colony. As
. Pathogenic micro-organisms, including bacteria and Protozoa; a practical manual for students, physicians and health officers. of the growthof the colonies. In many cases after a time concentric rings, in-creasing from day to day, appear in the zone of liquefaction. (SeeFigs. 144 and 145.) Examined under a low-power lens, at the endof sixteen to twenty-four hours, the colonies appear as small, light THE CHOLERA SPIRILLUM. 445 yellow, round, coarsely granular disks, with a more or less irregularoutline. In many cases at this stage an ill-defined halo is seen tosurround the granular colony. As the colonies become older thegranular structure increases, until a stage is reached when the surfacelooks as if it were covered with little fragments of broken glass. Lique-faction continues about the colonies, their structure appears fissuredand coarsely granular in texture, and occasionally a hair-like borderis formed at the periphery (Fig. 145). Sometimes the colonies maybe retained as compact masses in the zone of liquefaction, and thenthey are dark yellow or brown in color, and forms occur which are Fig. 144 Fig. 145.
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