. The basic aspects of radiation effects on living systems. Radiation -- Physiological effect. 340 SPECULATIONS ON CELLULAR ACTIONS we consider that a gene might be inactivated by a change in a relatively small chemical group in the gene "molecule," it seems reasonable that m might be quite small, perhaps unity. Some of the foregoing notions can be visualized qualitatively by ref- erence to Fig. 3. Two ionization tracks are shown crossing a single Fig. 3. Qualitative relations between a cell, two ionization tracks, and some relevant entities involved in the model of Fig. 1. Se
. The basic aspects of radiation effects on living systems. Radiation -- Physiological effect. 340 SPECULATIONS ON CELLULAR ACTIONS we consider that a gene might be inactivated by a change in a relatively small chemical group in the gene "molecule," it seems reasonable that m might be quite small, perhaps unity. Some of the foregoing notions can be visualized qualitatively by ref- erence to Fig. 3. Two ionization tracks are shown crossing a single Fig. 3. Qualitative relations between a cell, two ionization tracks, and some relevant entities involved in the model of Fig. 1. See text. The lower one has just been formed. Ions and excited fnolecules are present. The H2O"'' ions, which are assumed relevant to the specific action described in Fig. 1, are designated by circles and are all located directly in the path of the fast ionizing particle. All other entities pro- duced by the ionizing particle (all excited molecules and all ions except H2O''") are irrelevant and are designated by crosses. One possible path by which relevant entities may diffuse to the precursor is shown. Note that the H20'^ starts to diffuse and reacts to form an OH radical (one- pronged circle). The radical diffuses a bit and reacts to form a molecule of H2O2 (two-pronged circle) which finally, by diffusion, chances to col- lide and react with the precursor (decisive process). The upper track is older than the lower. All the relevant and irrelevant entities are sepa-. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Symposium on Radiobiology (1950 : Oberlin College); Nickson, James J. New York, Wiley
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