Manual of human histology . ish-red, sometimes brown, or even the latter case, a quantity of changed blood-corpuscles willbe met with (to which we shall return subsequently); in theformer, on the other hand, it may be microscopically demon-strated that the red colour proceeds from unchanged blood-cor-puscles, which may also be readily expressed from the sub-stance of the spleen and, on the addition of water, in ashort time lose all their colouring matter. In other animalsthe spleen, although it always has about the same, usuallydark colour, yet contains in addition, sometimes o


Manual of human histology . ish-red, sometimes brown, or even the latter case, a quantity of changed blood-corpuscles willbe met with (to which we shall return subsequently); in theformer, on the other hand, it may be microscopically demon-strated that the red colour proceeds from unchanged blood-cor-puscles, which may also be readily expressed from the sub-stance of the spleen and, on the addition of water, in ashort time lose all their colouring matter. In other animalsthe spleen, although it always has about the same, usuallydark colour, yet contains in addition, sometimes only un-changed blood-corpuscles, sometimes multitudes of them inevery stage of metamorphosis. These are very striking, andin all animals consist essentially in this—that, 1. the blood-corpuscles, becoming smaller and darker and, in the lowerVertebrata, losing their elliptical form and taking a circularshape, agglomerate together into rounded masses, which eitherpersist in this condition, or, combined with a certain amount. THE SPLEEN. 149 of the plasma of the blood, develope an envelope externallyand a nucleus in their interior, thus passing into round blood-corpuscle-holding cells, of 0005—0-015, containing 1—20 blood-corpuscles; and 2. these massesand cells, their contained blood-corpuscles gradually diminishingin size and assuming a goldenyellow, brownish-red, or blackcolour, either in their entire stateor after breaking up into pig-ment granules, change into ingment masses and pigmentedgranule cells; and, finally, the latter, their granules graduallybecoming pale, pass into perfectly colourless cells. In manycases the blood-corpuscles form no masses or cells, but passthrough the above-described stages of coloration and disintegra-tion, like the others. [The changes undergone by the blood in the spleen, a sub-ject which is more fully treated of in my Mikr. Anat.,^ II., 2,pp. 268-270, and which were observed and interpreted byEcker, at the same time and in the same mann


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Keywords: ., bookcentury1800, bookdecade1850, booksubjecthistolo, bookyear1853