Duodenal ulcer. Gross clinical specimen of part of a human duodenum (small intestine) with a perforated peptic ulcer (centre). Ulcers are caused by ex


Duodenal ulcer. Gross clinical specimen of part of a human duodenum (small intestine) with a perforated peptic ulcer (centre). Ulcers are caused by excessive stomach acid (digestive juice). This acid, often combined with excess alcohol and caffeine, attacks the gastrointestinal tract, causing pain and discomfort. If the wall's protective mucus has become thinner, possibly due to mental stress or bacterial attack, the acid can eventually perforate it, as in this case. Ulcers can be treated with antacid drugs that neutralise the stomach acid, but surgery may be required if the ulcer persists.


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