. A study of the causes underlying the origin of human monsters : third contribution to the study of the pathology of human embryos . the embryo below its attachment to the body immediately beneath the epidermis is a solid lentoid struc-ture. The skin is markedly thickened, the epidermis sometimesforming small papillae, or are sometimes buried, formingpear-like bodies similar to those of epithelial cancer, Within 254 MALL. [Vol. XIX. the body there is a large cavity filled with round cells. Nearthe attachment to the amnion there are several such abscess-like masses within the embry


. A study of the causes underlying the origin of human monsters : third contribution to the study of the pathology of human embryos . the embryo below its attachment to the body immediately beneath the epidermis is a solid lentoid struc-ture. The skin is markedly thickened, the epidermis sometimesforming small papillae, or are sometimes buried, formingpear-like bodies similar to those of epithelial cancer, Within 254 MALL. [Vol. XIX. the body there is a large cavity filled with round cells. Nearthe attachment to the amnion there are several such abscess-like masses within the embryo. The pigment dots, on account of their position, undoubt-edly represent the eyes of the embryo. Each forms a smallsac immediately below the skin filled with large free pigmentcells. Deeper within the head of the embryo a band ofpigment cells connects the two eyes, as may be the case ifwe consider these cells as the connecting optic nerves. No. 253. Ovum, 35 x 30 x 15 mm.; embryo, 4 Brodel, Baltimore. Chorion and villi are somewhat hyaline, with indications ofblood-vessels within them. Amnion, which measures 19 x. Fig. 253.—Embryo within the chorion,behind the embryo is the amnion. X 1-8 times. The collapsed bag 13 x 13 mm., is attached at one point, has hyaline walls anddoes not contain the embryo. The embryo is a swollen infiltrated specimen of the thirdweek, with no brain and little of its spinal cord left. The No. i.] ORIGIN OF HUMAN MONSTERS. 255 rest of the structures (heart, coelom and Wolffian body) arequite sharply defined, but are all infiltrated with round of the epidermis is intact. The arm buds are welldefined. No. 255. Ovum, 20 x 20 x 10 mm. Professor Brodel, Baltimore. The villi are atrophic and fibrous. At points the syncytiallayer is well mixed with leucocytes, which also have invadedsome of the villi as well as the mesoderm of the chorion. Thewhole chorion was cut into serial sections, but no trace of anembryo was. found. There are n


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