Practical pathology; a manual for students and practitioners . part of the convoluted tubule. nucleus situated in its centre. The upper part of the cell, that nearthe lumen, is finely granular, but the part between the nucleus and thebasement membrane is distinctly striated, the stride running longi-tudinally from the base of the cell to the nucleus. The next part ofthe tubule (the looped tubule of Henle) is principally within themedulla. The descending limb and the loop itself, (5) and (6), arelined by a layer of flattened epithelial cells. After the loop theascending limb of the tubule (7) i


Practical pathology; a manual for students and practitioners . part of the convoluted tubule. nucleus situated in its centre. The upper part of the cell, that nearthe lumen, is finely granular, but the part between the nucleus and thebasement membrane is distinctly striated, the stride running longi-tudinally from the base of the cell to the nucleus. The next part ofthe tubule (the looped tubule of Henle) is principally within themedulla. The descending limb and the loop itself, (5) and (6), arelined by a layer of flattened epithelial cells. After the loop theascending limb of the tubule (7) is lined with a layer of columnar I NORMAL STRUCTURE 365 cells, each of which has its nucleus placed near the lumen. Passingfurther upwards (8) the lumen becomes narrowed, but the epitheliumremains columnar. In the (9) the ascending tube is narrower,and its epithelium more cubical or flattened. Still in the cortex is(10) the irregular tubule, lined by columnar cells, which vary verymuch in height, always, however, leaving the lumen of this part of the. Fig. 100.—Looped tubules of Henle cut longitudinally in both ibeboundary layer and the papillary portion of the pyramid. ( x 100.) a. First part of the ascending limb of the looped tubule of Henle, in which the epithelium is columnar. b. Part of the ascending limb. c. The bend. d. The descending limb and loop of the looped tubule of Ilenle, in all of which the epithelium is flattened and tubules at these points are very like young blood vesselsin appearance. tubule very narrow. Then follows (11) the second or distal convolutedtubule, which is identical in position and structure with the firstpart of the convoluted tubule. After this, still in the cortex, are (12)the curved parts of the collecting tubule, and (13) part of the straighttubule, the lining of which is an irregular epithelium, with some ofthe cells cubical, others spindle-shaped, but all having well-marked 366 THE KIDNEY nuclei. Lower down in the


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