. Annals of surgery . tiology.—The etiology of this disease is in jiart still obscure. It iscertain that the predisposition to abnormal tenderness and the lack of resiStance of the mucous membrane may cause irritation of the oral cavity. Leucoplakia buccalis is essentially a disease of adults. So far as age isconcerned, it is most frequent in the fifth or sixth decade of life; it rarelyoccurs before the fortieth year. It is a rare occurrence in women (one tosixteen, according to Clark, and one to thirty-five, according to Leloir)According to Deboe, it exists only in men. It is described by som


. Annals of surgery . tiology.—The etiology of this disease is in jiart still obscure. It iscertain that the predisposition to abnormal tenderness and the lack of resiStance of the mucous membrane may cause irritation of the oral cavity. Leucoplakia buccalis is essentially a disease of adults. So far as age isconcerned, it is most frequent in the fifth or sixth decade of life; it rarelyoccurs before the fortieth year. It is a rare occurrence in women (one tosixteen, according to Clark, and one to thirty-five, according to Leloir)According to Deboe, it exists only in men. It is described by some writers as an occupational disease: The WhitePlaques of Glass-Blowers. Still other writers have regarded it as a consti-tutional disturbance. Arthritis and a variety of lierpes seem to play animportant r61e in the causation of a number of cases. Amemia, consumptiondiabetes, or any disturbance of digestion may be factors in the has been noted in connection with special irritative condition; 482. Fig. 8.—Cancer of the left half of the toileucoplakia and bilateral cervical adenopathy,in two sittings of the cervical and buccal glands on the right side were left in platiinatcly). Fulguration. March 21. lOoo. (nearly three years. LEUCOPLAKIA oi the digestive tract, such as dilatation of the stomach. In some instancesit api>ears to have developed as a result of the irritation of the tongue, dueto faulty dentition, or sharp corners of broken teeth. The habitual use ofalcohol is an undoubted factor and so also is the use of highly spiced andirritating foods and condiments. Protracted medication with such drugs as themercurials or the iodides are predisposing causes. So, also, is the habitualinhalation of smoke and dust. The principal cause is undoubtedly the smoking of many and strong cigarsor cigarettes, or the use of tobacco in short-stemmed pipes. The nicotine oftobacco is not the only cause, but the combustion products of the tobacc


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Keywords: ., bookcentury1800, bookdecade1880, booksubjectsurgery, bookyear1885