. The endocrine organs; an introduction to the study of internal secretion . such action only occurs in tissues whichare supplied with nerves from the sympathetic system, and in the embryoin these tissues only after they have received their nerve-supply (MFie).And, as has just been stated, severance of the nerves, so far from stoppingthe action, tends on the contrary to make the tissues supplied by thesevered nerve more easily excited by the autacoid. This has been found toapply not only to the blood-vessels, but also to the pupil (Meltzer and Auer)and to the retractor penis (Fletcher), and is
. The endocrine organs; an introduction to the study of internal secretion . such action only occurs in tissues whichare supplied with nerves from the sympathetic system, and in the embryoin these tissues only after they have received their nerve-supply (MFie).And, as has just been stated, severance of the nerves, so far from stoppingthe action, tends on the contrary to make the tissues supplied by thesevered nerve more easily excited by the autacoid. This has been found toapply not only to the blood-vessels, but also to the pupil (Meltzer and Auer)and to the retractor penis (Fletcher), and is probably of general and Chavasse have further shown that adrenalin acts upon themuscular coat of veins, causing tonic contraction of the peripheral veins andincreased rhythmic contraction of the superior vena cava near the heart. If the vagi are paralysed by atropine, as small a dose of adrenalin as -0003 milli-gramme per kilo body-weight injected into a rabbits vein will cause a distinct rise of Effects of Intravenous Injection of Suprarenal Extracts 61. FIG. 37. —Effect upon blood-pressure, kidney volume, and flow of urine of injecting suprarenal extract into the vein of a dog. (From Schafer and Herring, Phil. Trans., 1906.)A, tracing; B kidney volume change (oncograph): the full extent of the shrinkage is not recorded •3gnetOelectdc si«nal D- tine in -second larval. ; E, abscissa of A> FIG. 38. — Effect upon blood-pressure and limb volume of injecting suprarenal extract into a vein (dog). rhn^nf griterSV *? f*6!?-1 p™88nre : B> volume <han^s of left fors limb, nerves intact ; D, volumechanges of right fore limb, brachial plexus cut ; E, signal ; the line records abscissa of blood-pressure. 62 The Endocrine Organs arterial pressure (J. D. Cameron). Moore and Purinton found that with very minutedoses a fall of pressure may be obtained instead of a rise. If the amount injected isconsiderable, the rise of blood-pressure c
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