. Animal hormones; a comparative survey. Hormones. 198 METABOLIC HORMONES glucose. The optical isomers are unresponsive to insulin (Fig. 5-10). This suggests a point of further chemical attack upon the problem of the nature of the hormone action in lowering blood- sugars and making them available to the tissues; but the relation Insulin responsive. D-Glucose D-Galactose L-Arabinose Insiitin unresponsive ! CHO j CH2OH I CHO i HO—C—H 0=0 HO—C—H __j. [ , I 1 HO—C—H I I HO—C—H I H—C—OH H—C—OH H—C—OH H C—OH H—C—OH H—C—OH CH2OH CH2OH CH2OH D-Monnose D-Fructose D-Arobinose Fig. 5-10. The structure of
. Animal hormones; a comparative survey. Hormones. 198 METABOLIC HORMONES glucose. The optical isomers are unresponsive to insulin (Fig. 5-10). This suggests a point of further chemical attack upon the problem of the nature of the hormone action in lowering blood- sugars and making them available to the tissues; but the relation Insulin responsive. D-Glucose D-Galactose L-Arabinose Insiitin unresponsive ! CHO j CH2OH I CHO i HO—C—H 0=0 HO—C—H __j. [ , I 1 HO—C—H I I HO—C—H I H—C—OH H—C—OH H—C—OH H C—OH H—C—OH H—C—OH CH2OH CH2OH CH2OH D-Monnose D-Fructose D-Arobinose Fig. 5-10. The structure of some of the sugar molecules which have been found to be responsive to insulin and to resemble glucose in having the same side chains on the three terminal carbon atoms; and (below) three molecules of sugars which differ, however slightly, from glucose, and are found to be unresponsive to insulin (from Levine and Goldstein in Stetten and Bloom, 1955). of these facts to the known chemical structure of the insulin, which is a protein, is not yet within sight. The rate of secretion of insulin is self-regulating, in that a high level of blood-sugar increases insulin; and, as this lowers the level, so the insulin secretion itself is Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Jenkin, Penelope M. Oxford, New York, Pergamon Press
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Keywords: ., bookcentury1900, bookcollectionbiodiversity, booksubjecthormones