Intracholecystic papillary neoplasm, light micrograph

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Light micrograph of a haematoxylin and eosin-stained section of a gallbladder with intracholecystic papillary neoplasm (ICPN). The glands within ICPN show high-grade dysplasia. The nuclei are pleomorphic and have prominent nucleoli. Mitotic activity is brisk. ICPN is a macroscopic, non-invasive, papillary or polypoid epithelial tumour growing into the lumen of the gallbladder. It is considered premalignant and carries the risk of developing into invasive carcinoma.

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Photo credit: © WEBPATHOLOGY/SCIENCE PHOTO LIBRARY / Alamy / Afripics
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