The pathology and surgical treatment of tumors . nective tissue. 244 PATHOLOGY AND TREATMENT OF TUMORS. infiltration exclusively young epithelial cells which have left the primarytumor and are actively engaged in increasing its area. From the sur-face of the carcinoma there project into the surrounding tissue tumor-masses which render its surface uneven and nodular. These projectionsof the tumor can be seen to greatest advantage in squamous-celledcarcinoma. They appear first as conical or column-shaped infiltrationsconnected on one side with the primary tumor and projecting into theconnective
The pathology and surgical treatment of tumors . nective tissue. 244 PATHOLOGY AND TREATMENT OF TUMORS. infiltration exclusively young epithelial cells which have left the primarytumor and are actively engaged in increasing its area. From the sur-face of the carcinoma there project into the surrounding tissue tumor-masses which render its surface uneven and nodular. These projectionsof the tumor can be seen to greatest advantage in squamous-celledcarcinoma. They appear first as conical or column-shaped infiltrationsconnected on one side with the primary tumor and projecting into theconnective tissue on the other (Fig. 140). These projecting parts ofthe tumor impart to it from the very beginning a certain degree ofimmobility and cause the nodulated condition of its surface. The stimulation of the tissues caused by the invasion of so manyforeign bodies results also in the formation of new blood-vessels,brought about by a process of budding from the pre-existing blood-vessels adjacent to the tumor-matrix. The vascularization, not being. Fig. 141.—Deep-reaching epithelioma upon the leg, with papillary excrescences. Specimen from the part of the tumor which occupied the cavity in the tibia; X 6 (after Thiersch) : a, newvessels composed of numerous loops; b, elongated pedunculated proliferation of vessels; c, large vessel-trunks which suddenly terminate in capillaries ; d, compact masses of epithelial cells arranged in concentriclayers, cut transversely or obliquely, and surrounded by vascular stroma; e, part of a cleft-like cavity con-taining epithelial debris ; /, flat polygonal cells in irregular layers, answering to the horny epithelial cells ofthe skin ; g, layer of cells representing the rcte Malpighii. under the normal control of the nervous tissue, and being in a districtof planless tissue-proliferation, always assumes an atypical type. Theepithelial cells in carcinoma are brought in direct contact with the (Fig. 141, «^/). Th
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Keywords: ., bookcentury1800, bookdecade1890, booksubjectneoplas, bookyear1895
