. Ciba Foundation Symposium on the Regulation of Cell Metabolism. Cell metabolism. Phosphate Turnover and Pasteur Effect 268 the fact that it makes no difference whether the yeast cells are kept aerobically or anaerobically. Obviously the perme- ability of the cell membrane, which could control the sugar uptake, is independent of the gas phase. The peculiar form of the curve may be expressed by two. TOO 800 ' 900 1000 glucose cone. (^g/mJ.) Fig. 5. Comparison of uptake of glucose, fructose and mannose; aerobic. Experimental conditions as for Fig. 4. straight lines with different slopes (Figs.


. Ciba Foundation Symposium on the Regulation of Cell Metabolism. Cell metabolism. Phosphate Turnover and Pasteur Effect 268 the fact that it makes no difference whether the yeast cells are kept aerobically or anaerobically. Obviously the perme- ability of the cell membrane, which could control the sugar uptake, is independent of the gas phase. The peculiar form of the curve may be expressed by two. TOO 800 ' 900 1000 glucose cone. (^g/mJ.) Fig. 5. Comparison of uptake of glucose, fructose and mannose; aerobic. Experimental conditions as for Fig. 4. straight lines with different slopes (Figs. 4, 5). This suggests that two processes overlap when glucose enters the yeast cell. One process is probably an "active" transport and dominates in the range of small substrate,concentrations from zero up to 0-001 M glucose. Under the conditions of the experiments this mechanism can transport up to 5 [xmoles per minute per g. of wet yeast cells, which amounts to nearly half the saturation value. A second and much slower process is superimposed on the first one and can be assumed to be the passive sugar. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Ciba Foundation Symposium on the Regulation of Cell Metabolism (1958 : London, England); Wolstenholme, G. E. W. (Gordon Ethelbert Ward); O'Connor, Cecilia M. (Cecilia Mary), 1927-. Boston, Little, Brown


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