General and dental pathology with special reference to etiology and pathologic anatomy; a treatise for students and practitioners . , neuralgia and later atrophic ulcers make it moreserious than the nodular form. Anesthesia of the parts occurswhen the ulcerations develop. The two forms are often associated, and tuberculosis often fol-lows the lesions, especially those of the internal organs. Microscopically, the nodule is seen to be fibrous, somewhat vas-cular without tendency toward caseation. It is composed ofepithelioid cells (proliferated endothelium and connective tissuecells) which are o
General and dental pathology with special reference to etiology and pathologic anatomy; a treatise for students and practitioners . , neuralgia and later atrophic ulcers make it moreserious than the nodular form. Anesthesia of the parts occurswhen the ulcerations develop. The two forms are often associated, and tuberculosis often fol-lows the lesions, especially those of the internal organs. Microscopically, the nodule is seen to be fibrous, somewhat vas-cular without tendency toward caseation. It is composed ofepithelioid cells (proliferated endothelium and connective tissuecells) which are often vacuolated and may contain the bacilli;large degenerated cells (lepra cells) containing many bacilliand a few more or less degenerated nuclei are always cells are sometimes present, but far less often than in tu-berculosis. 1G8 GENERAL PATHOLOGY In the anesthetic form the bacilli grow within the sheaths ofnerves, forming fusiform swellings, resembling the nodules instructure. Skin eruptions (pemphigus leprosa) often occur, also atrophyof the parts affected, and sometimes even loss of parts, as fingersor Fig. C4.—Xodular leprosy. (Goldschmidt.) Syphilis, or Lues (or Great Pox) Syphilis is an infectious disease due to the presence of theSpirochete pallida, or Treponema It occurs in threestages. 2There is a tendency to place this organism among the protozoa. It is a rigid spiral, inmany respects resembling the spirilla, but it is claimed by some observers that inreproduction longitudinal division takes place, which would place the spirochete amongthe animal organisms. According to Jordan {General Bacteriology, 1918), At present thesystematic position of this organism may be regarded as unsettled, although the majorityof investigators incline to place it with the true bacteria, or at best in a group midwaybetween the bacteria and protozoa. PATHOLOGY OF [NFECTIOUS DISEASES 169 The primary stagi Is characterized by the chancre, which appearsafter
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Keywords: ., bookcentury1900, bookdecade1920, booksubjectpathology, bookyear19
