Report of first expedition to South America, 1913 . per cent,small mononuclears 12 per cent, eosinophils 0 per cent: Norm-oblasts 9 per cent, myelocytes per cent. Myelocytes arepresent in the severe cases ranging usually from to 2per cent. The hemoglobin in severe infections may amountto but 15 per cent. In less severe cases of infection it may befrom 40 to 50 per cent. In severe cases the parasites whichgive rise to the disease are present in the red cells in greatnumbers, but in mild cases the number of infected corpusclesis small and a long search is often necessary to disclose thep


Report of first expedition to South America, 1913 . per cent,small mononuclears 12 per cent, eosinophils 0 per cent: Norm-oblasts 9 per cent, myelocytes per cent. Myelocytes arepresent in the severe cases ranging usually from to 2per cent. The hemoglobin in severe infections may amountto but 15 per cent. In less severe cases of infection it may befrom 40 to 50 per cent. In severe cases the parasites whichgive rise to the disease are present in the red cells in greatnumbers, but in mild cases the number of infected corpusclesis small and a long search is often necessary to disclose theparasites. The following notes extracted from cases observedby us will serve to illustrate special clinical features of thedisease. 1 Bassett-Smith: Brit. M. J., Lond., 1909, ii, 783; Lancet, Lond., 1909, 461; Trop. Med. and Hyg., Lond., 1914, vii, 158. 2 Biffi: Bol. Acad, de med. de Lima, 1903, iii, 2. CLINICAL CHART DATE June ib, 1S13. Day of Month U27 2?2S30 I 2 5 Y 5 fc 7 8 «? 10 // /212 13 If 15 lb 17 l« n ZOll 22 23 2¥:i5 2t 27 22. N ^Cascixz- ffernicious OTOva FeveirL. ILLUSTRATIVE CASES 21 Cases Emphasizing Special Clinical FeaturesPernicious Oroya FeverCase Id. Pernicious Oroya Fever terminating in Death. — The patient,aged twenty-three years, a native of Austria, was received in the service ofDr. Arce in the Hospital Dos de Mayo of Lima, on June 26, 1913. We areindebted to Dr. Arce for notes regarding the history of this patient and forthe temperature record. The patient came to Peru in January, January, 1912, he suffered with malaria and anaemia. In Octoberhe had disturbance of the bladder. In April and May of 1913 he traveledon foot through the quehrada of Matucana, passing the night at San Barto-lome, which is known to be one of the most dangerous places in relation todisease in the verruga zone. In the middle of June he became sick withchills and fever, which attack he states lasted three days. Eight dayslater he tried to return to his work but


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