Kidney diseases, urinary deposits, and calculous disorders : their nature and treatment . ube has passed in its degeneration, which is quite at variance withthe views generally held. The changes seem to result simply fromwasting or shrinking of the secreting structure, while there is no evidencewhatever of the contraction of the matrix and the consequent constric-tion of the tubes at intervals, which has been generally acceptedas the explanation of the change. The largest tubes are usually filledwith wide transparent casts. The epithelium is usually very narrow, the cells small and irregularly
Kidney diseases, urinary deposits, and calculous disorders : their nature and treatment . ube has passed in its degeneration, which is quite at variance withthe views generally held. The changes seem to result simply fromwasting or shrinking of the secreting structure, while there is no evidencewhatever of the contraction of the matrix and the consequent constric-tion of the tubes at intervals, which has been generally acceptedas the explanation of the change. The largest tubes are usually filledwith wide transparent casts. The epithelium is usually very narrow, the cells small and irregularlyscattered. Sometimes all traces of epithelium disappear from someparts of the tubes, and in place of this is found a large quantity ofactively growing germinal matter, which increases so as to form largecollections from which buds or offsets proceed as in fig. 63. Thusnew growth occurs. After a time, perhaps from the supply of nutrientmatter being cut off, this germinal matter dies, and large oil globulesresult. These collect in patches. In some of the partially wasted tubes ? I - I. 6 t, with o ? -rieialiy ae, 6, small5. pp. 63,84.
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