Transactions . ,Schlemms canal (Figs. I, III, and VI, Sc) is not involved,except as it appears to be a little flattened as a result of pres-sure. The iris throughout is somewhat infiltrated, and notably soin the region of the hypopyon, where the leucocytes and fibrincrowd everywhere between the normal tissue elements (,//). In the posterior chamber there is no evidence of any dis-turbance, except that in the extreme lower angle, just behindthe root of the iris, and among the sulci of the ciliary processes,there are a few leucocytes, but no fibrin (Fig. VI, Z). Thereis also a possible dis
Transactions . ,Schlemms canal (Figs. I, III, and VI, Sc) is not involved,except as it appears to be a little flattened as a result of pres-sure. The iris throughout is somewhat infiltrated, and notably soin the region of the hypopyon, where the leucocytes and fibrincrowd everywhere between the normal tissue elements (,//). In the posterior chamber there is no evidence of any dis-turbance, except that in the extreme lower angle, just behindthe root of the iris, and among the sulci of the ciliary processes,there are a few leucocytes, but no fibrin (Fig. VI, Z). Thereis also a possible disturbance of the pigment layer, indicated bya shower of pigment granules along the posterior surface ofthe iris. The deeper portions of the globe are normal. No cultures were taken from the ulcer, and none of theordinary staining methods have given any satisfactory bacterio-logical results. The prevailing older idea was that hypopyon is derivedeither directly from the cornea, because of the string of pus F Z?;Ai. Fig. VI. C, cornea; Cb, ciliary body; Dm, DescemeVs membrane; E, E\, endothelium of Descemettmembrane; F, fibrin; ff, hupojiycn; I, iris; L, leucocytes; S, sclera; Sc, Schlemms canal. Green and Ewing : Hypopyon-Keratitis. 721 that is often seen in the anterior chamber descending fromthe purulent mass, or else from the iris, the anterior chamberbeing regarded as a serous cavity capable of furnishing anexudate as in the case of the pleura or the peritoneum (Ward-rop, 1808). Later writers have explained the formation ofhypopyon in different ways, namely : (i) By the direct passage of leucocytes through Des-cemets membrane. ( Zur Lehre von der Hypopyon-Keratitis,Marie Bokowa, Zurich, 1871.) (2) By passing around Descemets membrane, the leuco-cytes traveling downward through the corneal tissue and press-ing into the anterior chamber through the openings in theligamentum pectinatum. (Schweigger, Handbuch der Augen-heilkunde, II Aufl., 1873, page 307.) (3) By leuc
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