. Epilepsy, a study of the idiopathic disease. on in the numberof granules. In the atrophied foliae, according to the extent ofthe lesion, there are few or none of either Purkinje cells orgranules. Evidences of intra-vascular coagulation (Fig. 6) are abundant,and, although so far no actual demonstration of rupture due toblocked circulation has been met with here, the often limited,and always sharply defined, area of atrophy is strongly in favourof the lesion being due to deprivation of,the blood supply. Medulla oblongata. This was the favourite site for thelocalisation of the essential lesions
. Epilepsy, a study of the idiopathic disease. on in the numberof granules. In the atrophied foliae, according to the extent ofthe lesion, there are few or none of either Purkinje cells orgranules. Evidences of intra-vascular coagulation (Fig. 6) are abundant,and, although so far no actual demonstration of rupture due toblocked circulation has been met with here, the often limited,and always sharply defined, area of atrophy is strongly in favourof the lesion being due to deprivation of,the blood supply. Medulla oblongata. This was the favourite site for thelocalisation of the essential lesions of epilepsy by the olderpathologists, and they were able to demonstrate here manyfairly constant and well-marked changes, such as sclerosis andconstant engorgement of the vessels, with not infrequentlypunctate haemorrhages. Schroder van der Kolk ^ accountedfor the sclerosis by an exudation of albumen from the distendedvessels, the exudation subsequently undergoing fatty degenera- ^ Kolk, Schroder van der, Neiu Syd. Soc. Trans., 1859, Fig. 3. cell from a case of eisileptlc Idiocy, with enormously swollen bladder-like nucleus. This form, which is commonly met with iu epileptics, bearsa great resemblance to the cortical nerve cells of a dog after ligature of itscerebral vessels.
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