. The elements of experimental embryology. Embryology, Experimental; Embryology. a b c Fig. 180 Diagram showing the effect on the differentiation of the neural tube of a, proxi- mity of a notochord without myotomes; b, proximity of myotomes without notochord; c, absence of notochord and myotomes (mesenchymal environment); as seen in transverse section. (From Holtfreter, Arch. Entwmech. cxxvii, 1933.) At the same time, certain features of the differentiation of the neural tube are not independent of the presence of other structures. For instance, the notochord is responsible for the formation o
. The elements of experimental embryology. Embryology, Experimental; Embryology. a b c Fig. 180 Diagram showing the effect on the differentiation of the neural tube of a, proxi- mity of a notochord without myotomes; b, proximity of myotomes without notochord; c, absence of notochord and myotomes (mesenchymal environment); as seen in transverse section. (From Holtfreter, Arch. Entwmech. cxxvii, 1933.) At the same time, certain features of the differentiation of the neural tube are not independent of the presence of other structures. For instance, the notochord is responsible for the formation of the ventral sulcus of the central canal, it determines the formation of a thin floor on the side of the neural tube immediately overlying it.^ On the other hand, the myotomes which flank the neural tube are responsible for the formation of the thick lateral walls, and for the radial arrangement of the cells in them^. These facts emerge from experiments in which embryos were obtained possessing a notochord but no myotomes, or with myotomes but no notochord. It will be noticed that the action on the differentiation of the neural tube of both notochord and myotomes tends to the same result. If Nicholas, 1930. Coghill, 1929; Detwiler, several works. ^ Mangold and Seidel, 1927; Bautzmann, 1928; Bytinski-Salz, 1929. * Lehmann, Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Huxley, Julian, 1887-1975; De Beer, Gavin, Sir, 1899-1972. New York [Hafner Pub. Co. ]
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